The purpose of the VIA Interventions Study is to evaluate the safety of a cocktail of compounds that, individually, have been shown to increase healthspan and/or lifespan in model organisms. These compounds are classified as supplements or drugs. All of the supplements are listed as Generally Recognized as Safe by the FDA. All of the drugs are FDA-approved to treat a recognized human disease.
This study is unique: Never before have these compounds been administered in combination to humans. Because the FDA does not consider aging a disease, no pharmacological studies in humans have been conducted to target “aging.”
This VIA Interventions Study is historic, even though all of the compounds are GRAS supplements or FDA-approved drugs. It is the first clinical trial where a cocktail of drugs that mimic calorie restriction have been combined with treatments targeting pathways not directly related to CR – such as anti-inflammaging compounds and senolytics – in order to treat “aging”.
Before you can be enrolled in the VIA Interventions Trial, you must have already enrolled in the VIA Longitudinal Study.
Those who have enrolled in the VIA Longitudinal Study have already completed a health questionnaire, undergone cognitive testing, undergone physiologic function testing, whole genome sequencing, body composition analysis testing (DEXA scan), and have a panel of blood tests done. These tests are designed to ensure that you are healthy and will not have a condition that would skew the results of a health aging study
You qualify for the VIA Interventions Trial if are 50 years of age or older, you are generally healthy, you have the legal ability to make your own decisions, and you have expressed an interest in volunteering for this study. Those are the main inclusion criteria for joining this study. There are no restrictions of race, gender, ethnicity, socioeconomic status, educational status, sexual preference, religious preference, or political views in this study. On the contrary, we are actively recruiting a large cohort of aging healthy volunteers that are racially, ethnically, and gender diverse; with an emphasis on groups that face health disparities as well as LGBT groups.